Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
PDIA1 | - |
Homo sapiens |
protein disulfide isomerase A1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme inhibition results ina 25% loss of vessel caliber post-injury. This is accompanied by decreased hydrogen peroxide formation and changes in collagen organization, resulting in increased arterial stiffness | Homo sapiens |
physiological function | the enzyme is a regulatorof vessel architecture and circumference that prevents inward remodeling without effects on wall thickness or neointima formation | Homo sapiens |