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Literature summary for 5.3.4.1 extracted from
- Protein disulfide isomerase isomerizes non-native disulfide bonds in human proinsulin independent of its peptide-binding activity (2011), Protein Sci., 20, 588-596.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 56300 | - |
1 * 56300, calculated from amino acid sequence | Homo sapiens |
| 57700 | - |
1 * 57700, analytical ultracentrifugation | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Insulin-(SS) + GSH | Homo sapiens | protein disulfide isomerase supports proinsulin folding as chaperone and isomerase | Insulin-(SH)2 + GSSG | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Insulin-(SS) + GSH | protein disulfide isomerase supports proinsulin folding as chaperone and isomerase | Homo sapiens | Insulin-(SH)2 + GSSG | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 56300, calculated from amino acid sequence | Homo sapiens |
| monomer | 1 * 57700, analytical ultracentrifugation | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDI | - |
Homo sapiens |
| protein disulfide isomerase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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