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Literature summary for 5.3.4.1 extracted from

  • Ado, K.; Takeda, N.; Kikuchi, M.; Taniguchi, Y.
    The pressure effect on the structure and functions of protein disulfide isomerase (2006), Biochim. Biophys. Acta, 1764, 586-592.
    View publication on PubMed
Search for more literature for 5.3.4.1

Activating Compound

Activating Compound Comment Organism Structure
GSH
-
 Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
additional information pressure conditions at 400 MPa decrease the enzyme isomerase activity Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 x * 55000, SDS-PAGE Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
native enzyme Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
insulin reduction of sidulfide bonds Bos taurus ?
-
 ?
additional information the enzyme shows disulfide reduction and chaperone activities and contains a WCGHC active site, overview, tertiary structure and function analysis under pressure conditions above 100 MPa, overview Bos taurus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 55000, SDS-PAGE Bos taurus
More a multidomain protein, tertiary structure and function analysis under pressure conditions above 100 MPa, overview Bos taurus

Synonyms

Synonyms Comment Organism
PDI
-
 Bos taurus
protein disulfide isomerase
-
 Bos taurus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
45
-
 assay at Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Bos taurus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Bos taurus