Literature summary for 5.3.3.9 extracted from

Polet, H.; Levine, L.
Partial purification and characterization of prostaglandin A isomerase from rabbit serum (1975), Arch. Biochem. Biophys., 168, 96-103.

Search for more literature for 5.3.3.9

General Stability

General Stability	Organism
8 M urea completely and irreversibly inactivates	Oryctolagus cuniculus

Inhibitors

Inhibitors	Comment	Organism	Structure
NEM	-	Oryctolagus cuniculus
Urea	8 M, completely and irreversibly inactivates	Oryctolagus cuniculus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.05	-	prostaglandin A1	in presence of rabbit albumin	Oryctolagus cuniculus
0.04	-	prostaglandin A1	in absence of rabbit albumin	Oryctolagus cuniculus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
110000	-	gel filtration	Oryctolagus cuniculus

Organism

Organism	UniProt	Comment	Textmining
Oryctolagus cuniculus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
partial	Oryctolagus cuniculus

Source Tissue

Source Tissue	Comment	Organism	Textmining
serum	-	Oryctolagus cuniculus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.133	-	-	Oryctolagus cuniculus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(13E)-(15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid	i.e. prostaglandin A1	Oryctolagus cuniculus	(13E)-(15S)-15-Hydroxy-9-oxoprosta-8[12]13-dien-1-oic acid	-	?
prostaglandin A1	-	Oryctolagus cuniculus	?	-	?

Temperature Stability [°C]

Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
65	-	20 min, inactivation	Oryctolagus cuniculus

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Release 2022.2 (July 2022)