Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.3.3.8 extracted from

  • Kilponen, J.M.; Hiltunen, J.K.
    beta-Oxidation of unsaturated fatty acids in humans. Isoforms of DELTA3,DELTA2-enoyl-CoA isomerase (1993), FEBS Lett., 322, 299-303.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
2 * 30000, myocardium, SDS-PAGE Homo sapiens
70000
-
myocardium, dimeric enzyme, gel filtration Homo sapiens
70000
-
liver, monomeric enzyme, gel filtration Homo sapiens
78000
-
1 * 78000, liver, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
at least 2 isoforms in liver: 1. monofunctional mitochondrial enzyme, 2. peroxisomal enzyme forming a part of a multifunctional enzyme
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Homo sapiens
-
liver at least 2 isoforms in liver: 1. monofunctional mitochondrial enzyme, 2. peroxisomal enzyme forming a part of a multifunctional enzyme Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-trans-Decenoyl-CoA
-
Homo sapiens 2-trans-Decenoyl-CoA
-
?
3-trans-dodecenoyl-CoA
-
Homo sapiens 2-trans-dodecenoyl-CoA
-
?
3-trans-Hexenoyl-CoA
-
Homo sapiens 2-trans-Hexenoyl-CoA
-
?
additional information the velocity ratios with 3-trans-C6:C10:C12-enoyl-CoA is 1:2.1:1.2 for the liver enzyme and 1:3.4:2.3 for the heart enzyme Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 30000, myocardium, SDS-PAGE Homo sapiens
monomer 1 * 78000, liver, SDS-PAGE Homo sapiens