Crystallization (Comment) | Organism |
---|---|
hanging drop vapor diffusion method, crystal structure of the C67A mutant of isopentenyl diphosphate isomerase complexed with the mechanism-based irreversible inhibitor 3,4-epoxy-3-methyl-1-butyl diphosphate | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,4-epoxy-3-methyl-1-butyl diphosphate | - |
Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Escherichia coli | key enzyme in biosynthesis of isoprenoids | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
Isopentenyl diphosphate = dimethylallyl diphosphate | the mechanism of isomerizaion reaction involves protonation of the unactivated carbon-carbon double bond in the substrate, Glu116 is involved in the protonation step and Cys67 is involved in the elimination step | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | key enzyme in biosynthesis of isoprenoids | Escherichia coli | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IPP:DMAPP | - |
Escherichia coli |