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Literature summary for 5.3.3.12 extracted from

  • Aroca, P.; Garcia-Borron, J.C.; Solano, F.; Lozano, J.A.
    Regulation of mammalian melanogenesis I: partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase (1990), Biochim. Biophys. Acta, 1035, 266-275.
    View publication on PubMed
Search for more literature for 5.3.3.12

Inhibitors

Inhibitors Comment Organism Structure
indole
-
 Mus musculus
additional information unaffected by metal chelators Mus musculus
tryptophan
-
 Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 dopachrome pH 6.0, 30°C Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-
melanosome preferentially associated to, but also found in microsomal and cytosolic fractions Mus musculus 42470
-
microsome
-
 Mus musculus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46000
-
 x * 46000, SDS-PAGE Mus musculus
300000
-
 gel filtration Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
melanoma cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dopachrome
-
 Mus musculus 5,6-dihydroxyindole-2-carboxylate
-
 ?

Subunits

Subunits Comment Organism
? x * 46000, SDS-PAGE Mus musculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Mus musculus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2
-
 tryptophan
-
 Mus musculus