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BRENDA support

Literature summary for 5.3.3.1 extracted from

  • Jha, S.K.; Ji, M.; Gaffney, K.J.; Boxer, S.G.
    Site-specific measurement of water dynamics in the substrate pocket of ketosteroid isomerase using time-resolved vibrational spectroscopy (2012), J. Phys. Chem. B, 116, 11414-11421.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
D40N the mutation does not perturb the gross tertiary and secondary structure of the enzyme The D40N mutant mimics the charge distribution of the enzyme active site in the intermediate state (protonated base), and is not the active form of the enzyme Pseudomonas putida

Organism

Organism UniProt Comment Textmining
Pseudomonas putida
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Synonyms

Synonyms Comment Organism
DELTA5-3-keto steroid isomerase
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Pseudomonas putida
KSI
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Pseudomonas putida