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Literature summary for 5.3.3.1 extracted from
- Water in the active site of ketosteroid isomerase (2011), Biochemistry, 50, 6689-6700.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| Y16F | the number of water molecules directly hydrogen bonded to the ligand oxygen is one in the Y16F mutant | Pseudomonas putida |
| Y16F/Y32F/Y57F | the number of water molecules directly hydrogen bonded to the ligand oxygen is one in the Y16F/Y32F/Y57F mutant | Pseudomonas putida |
| Y16S | the number of water molecules directly hydrogen bonded to the ligand oxygen is approximately two in the Y16S mutant | Pseudomonas putida |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas putida | P07445 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5,10-estrene-3,17-dione | - |
Pseudomonas putida | ? | - |
? |  |
| 5-Androstene-3,17-dione | - |
Pseudomonas putida | 4-Androstene-3,17-dione | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DELTA5-3-ketosteroid isomerase | - |
Pseudomonas putida |
| KSI | - |
Pseudomonas putida |
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