Literature summary for 5.3.3.1 extracted from

Bevins, C.L.; Pollack, R.M.; Kayser, R.H.; Bounds, P.L.
Detection of transient enzyme-steroid complex during active-site-directed irreversible inhibition of 3-oxo-DELTA5-steroid isomerase (1986), Biochemistry, 25, 5159-5164.

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Inhibitors

Inhibitors	Comment	Organism	Structure
(17S)-Spiro[5alpha-androstane-17,2'-oxiran]-3-one	potent irreversible active-site directed	Comamonas testosteroni
(17S)-Spiro[estra-1,3,5(10),6,8-pentaene-17,2'-oxiran]-3-ol	active-site-directed, irreversible	Comamonas testosteroni
(17S)-Spiro[estra-1,3,5(10)-triene-17,2'-oxiran]-3-ol	potent irreversible active-site directed	Comamonas testosteroni

Organism

Organism	UniProt	Comment	Textmining
Comamonas testosteroni	-	-	-

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Release 2023.1 (January 2023)