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Literature summary for 5.3.2.1 extracted from

  • Zang, X.; Taylor, P.; Wang, J.M.; Meyer, D.J.; Scott, A.L.; Walkinshaw, M.D.; Maizels, R.M.
    Homologues of human macrophage migration inhibitory factor from a parasitic nematode. Gene cloning, protein activity, and crystal structure (2002), J. Biol. Chem., 277, 44261-44267.
    View publication on PubMed
Search for more literature for 5.3.2.1

Cloned(Commentary)

Cloned (Comment) Organism
-
 Brugia malayi

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapor diffusion method, crystal structure of Bm-MIF-2 at 1.8 A resolution reveals a trimeric assembly with an inner pore created by beta-stranded sheets from each subunit Brugia malayi

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
13100
-
 x * 13100, Bm-MIF-2, calculation from nucleotide sequence Brugia malayi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Brugia malayi the enzyme is chemotactic for human monocytes and activates them to produce IL-8, TNF-alpha and endogenous MIF ?
-
 ?

Organism

Organism UniProt Comment Textmining
Brugia malayi Q9NAS2
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is chemotactic for human monocytes and activates them to produce IL-8, TNF-alpha and endogenous MIF Brugia malayi ?
-
 ?

Subunits

Subunits Comment Organism
? x * 13100, Bm-MIF-2, calculation from nucleotide sequence Brugia malayi