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Literature summary for 5.3.1.9 extracted from

  • Milewski, S.; Janiak, A.; Wojciechowski, M.
    Structural analogues of reactive intermediates as inhibitors of glucosamine-6-phosphate synthase and phosphoglucose isomerase (2006), Arch. Biochem. Biophys., 450, 39-49.
    View publication on PubMed
Search for more literature for 5.3.1.9

Inhibitors

Inhibitors Comment Organism Structure
2-amino-2-deoxy-D-glucitol 6-phosphate comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
2-amino-2-deoxy-D-glucitol 6-phosphate dimethyl ester comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
2-amino-2-deoxy-D-mannitol 6-phosphate comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
2-Deoxy-D-glucitol 6-phosphate comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
5-phospho-D-arabinoamide comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
5-phospho-D-arabinoate comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
5-phospho-D-arabinohydroxamate comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
6-phospho-D-gluconate comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
6-phospho-D-gluconoamide comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
D-glucitol 6-phosphate comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae
N-acetyl-2-amino-2-deoxy-D-glucitol 6-phosphate comparison with inhibition of Candida albicans D-glucosamine 6-phosphate synthase Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose 6-phosphate
-
 Saccharomyces cerevisiae D-glucose 6-phosphate
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0022
-
 5-phospho-D-arabinoate pH 8.0 Saccharomyces cerevisiae
0.0046
-
 5-phospho-D-arabinoamide pH 8.0 Saccharomyces cerevisiae
0.04
-
 D-glucitol 6-phosphate pH 8.0 Saccharomyces cerevisiae
0.076
-
 N-acetyl-2-amino-2-deoxy-D-glucitol 6-phosphate pH 8.0 Saccharomyces cerevisiae
0.148
-
 6-phospho-D-gluconate pH 8.0 Saccharomyces cerevisiae
0.56
-
 6-phospho-D-gluconoamide pH 8.0 Saccharomyces cerevisiae
0.68
-
 2-Deoxy-D-glucitol 6-phosphate pH 8.0 Saccharomyces cerevisiae
12.3
-
 2-amino-2-deoxy-D-glucitol 6-phosphate pH 8.0 Saccharomyces cerevisiae
17.2
-
 2-amino-2-deoxy-D-mannitol 6-phosphate pH 8.0 Saccharomyces cerevisiae