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Literature summary for 5.3.1.9 extracted from
- Phosphoglucose isomerase from Escherichia coli K10: purification, properties and formation under aerobic and anaerobic conditions (1980), Arch. Microbiol., 127, 289-298.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 6-phosphogluconate | - |
Escherichia coli |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.2 | - |
fructose 6-phosphate | enzyme forms PGI I and PGI II | Escherichia coli | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 59000 | - |
2 * 59000, low-molecular weight form, SDS-PAGE | Escherichia coli |
| 59000 | - |
possible 4 * 59000, high-molecular weight form, SDS-PAGE | Escherichia coli |
| 120000 | 130000 | low-molecular weight form PGI I, gel filtration, sucrose density gradient centrifugation | Escherichia coli |
| 220000 | 234000 | high-molecular weight form PGI II, gel filtration | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Escherichia coli | the formation of phosphoglucose isomerase is under respiratory control, during anaerobiosis the enzyme is derepressed parallely with other glycolytic enzymes | ? | - |
? | |
| additional information | Escherichia coli K10 | the formation of phosphoglucose isomerase is under respiratory control, during anaerobiosis the enzyme is derepressed parallely with other glycolytic enzymes | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
K10 | - |
| Escherichia coli K10 | - |
K10 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 2 forms: low-molecular weight form PGI I, and high-molecular weight form PGI II | Escherichia coli |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the formation of phosphoglucose isomerase is under respiratory control, during anaerobiosis the enzyme is derepressed parallely with other glycolytic enzymes | Escherichia coli | ? | - |
? | |
| additional information | the formation of phosphoglucose isomerase is under respiratory control, during anaerobiosis the enzyme is derepressed parallely with other glycolytic enzymes | Escherichia coli K10 | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 59000, low-molecular weight form, SDS-PAGE | Escherichia coli |
| tetramer | possible 4 * 59000, high-molecular weight form, SDS-PAGE | Escherichia coli |
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