Application | Comment | Organism |
---|---|---|
synthesis | inactivation of the manA gene encoding phosphomannose isomerase results in production of amphotericins and their aglycones, 8-deoxyamphoteronolides. A double mutant lacking the phosphomannose isomerase and phosphomannomutase genes produces 8-deoxyamphoteronolides in good yields along with trace levels of glycosylated amphotericins | Streptomyces nodosus |
Cloned (Comment) | Organism |
---|---|
- |
Streptomyces nodosus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | inactivation of the manA gene encoding phosphomannose isomerase results in production of amphotericins and their aglycones, 8-deoxyamphoteronolides. A double mutant lacking the phosphomannose isomerase and phosphomannomutase genes produces 8-deoxyamphoteronolides in good yields along with trace levels of glycosylated amphotericins | Streptomyces nodosus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces nodosus | - |
- |
- |