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Literature summary for 5.3.1.6 extracted from

  • de V. C. Sinatti, V.; R. Baptista, L.; Alves-Ferreira, M.; Dardenne, L.; HermÃxadnio Martins da Silva, J.; Guimarães, A.
    In silico identification of inhibitors of ribose 5-phosphate isomerase from Trypanosoma cruzi using ligand and structure based approaches (2017), J. Mol. Graph. Model., 77, 168-180 .
    View publication on PubMed
Search for more literature for 5.3.1.6

Inhibitors

Inhibitors Comment Organism Structure
(2R,3S)-3-hydroxy-1-(6-oxo-1,4,5,6-tetrahydropyridazine-3-carbonyl)pyrrolidine-2-carboxylic acid inhibitor identified by in silico analysis, shows best docking score of -12.735 forming six hydrogen bonds and one salt bridge Trypanosoma cruzi
[(2R,3S,4R,5R,6S)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl hydrogen sulfate inhibitor identified by in silico analysis, second best hit with dock-ing score of -11.927 and is predict to make eight hydrogenbonds, two electrostatic interactions and one possible pi-pi interaction Trypanosoma cruzi

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi Q4CQE2
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Trypanosoma cruzi CL Brener Q4CQE2
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Synonyms

Synonyms Comment Organism
Tc00.1047053509199.24
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 Trypanosoma cruzi