Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.3.1.24 extracted from

  • Leopoldseder, S.; Claren, J.; Jurgens, C.; Sterner, R.
    Interconverting the catalytic activities of (betaalpha)(8)-barrel enzymes from different metabolic pathways: sequence requirements and molecular analysis (2004), J. Mol. Biol., 337, 871-879.
    View publication on PubMed
Search for more literature for 5.3.1.24

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.026
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127G, mutant form of EC 5.3.1.6 Thermotoga maritima
0.03
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127K, mutant form of EC 5.3.1.6 Thermotoga maritima
0.04
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D130P, mutant form of imidazole glycerol phosphate synthase Thermotoga maritima
0.041
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127F, mutant form of EC 5.3.1.6 Thermotoga maritima
0.043
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127T, mutant form of EC 5.3.1.6 Thermotoga maritima
0.045
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D130T, mutant form of imidazole glycerol phosphate synthase Thermotoga maritima
0.051
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127V/T164H, mutant form of EC 5.3.1.6 Thermotoga maritima
0.074
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127V, mutant form of EC 5.3.1.6 Thermotoga maritima
0.074
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D130V, mutant form of imidazole glycerol phosphate synthase Thermotoga maritima

Organism

Organism UniProt Comment Textmining
Thermotoga maritima
-
 imidazole glycerol phosphate synthase mutant enzyme forms that generate phosphoribosylanthranilate isomerase activity: D130V, D130T, D130P. Mutant form of EC 5.3.1.6 that generate phosphoribosylanthranilate isomerase activity: D127V, D127K, D127T, D127G, D127F, D127V/T164H
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-(5-phospho-beta-D-ribosyl)anthranilate imidazole glycerol phosphate synthase mutant enzyme forms that generate phosphoribosylanthranilate isomerase activity: D130V, D130T, D130P. Mutant form of EC 5.3.1.6 that generate phosphoribosylanthranilate isomerase activity: D127V, D127K, D127T, D127G, D127F, D127V/T164H Thermotoga maritima 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
More imidazole glycerol phosphate synthase mutant enzyme forms that generate phosphoribosylanthranilate isomerase activity: D130V, D130T, D130P. Mutant form of EC 5.3.1.6 that generate phosphoribosylanthranilate isomerase activity: D127V, D127K, D127T, D127G, D127F, D127V/T164H Thermotoga maritima

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.000092
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D130T, mutant form of imidazole glycerol phosphate synthase Thermotoga maritima
0.00018
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D130V, mutant form of imidazole glycerol phosphate synthase Thermotoga maritima
0.00022
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D130P, mutant form of imidazole glycerol phosphate synthase Thermotoga maritima
0.0013
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127G, mutant form of EC 5.3.1.6 Thermotoga maritima
0.0017
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127K, mutant form of EC 5.3.1.6 Thermotoga maritima
0.0023
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127F, mutant form of EC 5.3.1.6 Thermotoga maritima
0.0027
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127T, mutant form of EC 5.3.1.6 Thermotoga maritima
0.0086
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127V, mutant form of EC 5.3.1.6 Thermotoga maritima
0.009
-
 N-(5-phospho-beta-D-ribosyl)anthranilate pH 7.5, 25°C, D127V/T164H, mutant form of EC 5.3.1.6 Thermotoga maritima