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Literature summary for 5.3.1.22 extracted from

  • Navone, L.; Macagno, J.P.; Licona-Cassani, C.; Marcellin, E.; Nielsen, L.K.; Gramajo, H.; Rodriguez, E.
    AllR controls the expression of Streptomyces coelicolor allantoin pathway genes (2015), Appl. Environ. Microbiol., 81, 6649-6659 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.3.1.22

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
55
-
 Hydroxypyruvate pH 7.0, 30°C Streptomyces coelicolor

Organism

Organism UniProt Comment Textmining
Streptomyces coelicolor Q9Z596
-
-
Streptomyces coelicolor ATCC BAA-471 Q9Z596
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Hydroxypyruvate
-
 Streptomyces coelicolor 2-Hydroxy-3-oxopropanoate
-
 ?
Hydroxypyruvate
-
 Streptomyces coelicolor ATCC BAA-471 2-Hydroxy-3-oxopropanoate
-
 ?

Synonyms

Synonyms Comment Organism
hyi
-
 Streptomyces coelicolor
SCO6206
-
 Streptomyces coelicolor

Expression

Organism Comment Expression
Streptomyces coelicolor AllR is a negative regulator of the allantoin pathway, binding to the promoter regions of allantoin catabolic genes down

General Information

General Information Comment Organism
physiological function among all genes from the allantoin pathway that are upregulated in the regulator AllR mutant, the Hyi gene encoding a hydroxypyruvate isomerase is responsible of the impairment of antibiotic production Streptomyces coelicolor