Any feedback?
Literature summary for 5.3.1.1 extracted from
- wasted away, a Drosophila mutation in triosephosphate isomerase, causes paralysis, neurodegeneration, and early death (2006), Proc. Natl. Acad. Sci. USA, 103, 14987-14993.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | mutation wasted away is a recessive, hypomorphic mutation that causes progressive motor impairment, vacuolar neuropthology, and severely reduced lifespan. Mutation affects the gene for triosephosphate isomerase. There is no genetic evidence that the mutation leads to misfolded or aberrant protein. Mutation may lead to an accumulation of methylglyoxal and the consequent enhanced production of advanced glycation end products | Drosophila melanogaster |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | - |
- |
- |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
