Cloned (Comment) | Organism |
---|---|
- |
Trypanosoma cruzi |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
methyl methanethiosulfonate | the sensitivity of enzyme from Trypanosoma cruzi is about 40times higher than that of Trypanosoma brucei and 200times higher than that of Leishmania mexicana | Leishmania mexicana | |
methyl methanethiosulfonate | the sensitivity of enzyme from Trypanosoma cruzi is about 40times higher than that of Trypanosoma brucei and 200times higher than that of Leishmania mexicana | Trypanosoma brucei | |
methyl methanethiosulfonate | the sensitivity of enzyme from Trypanosoma cruzi is about 40times higher than that of Trypanosoma brucei and 200times higher than that of Leishmania mexicana | Trypanosoma cruzi |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.6 | - |
D-glyceraldehyde 3-phosphate | D-glyceraldehyde 3-phosphate | Trypanosoma brucei | |
0.9 | - |
D-glyceraldehyde 3-phosphate | - |
Trypanosoma cruzi | |
0.9 | - |
D-glyceraldehyde 3-phosphate | - |
Leishmania mexicana |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
27244 | - |
2 * 27244, calculation from nucleotide sequence | Trypanosoma cruzi |
50000 | - |
gel filtration | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania mexicana | - |
- |
- |
Trypanosoma brucei | - |
- |
- |
Trypanosoma cruzi | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Trypanosoma cruzi |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
3527 | - |
- |
Trypanosoma cruzi |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-Glyceraldehyde 3-phosphate | - |
Trypanosoma brucei | Glycerone phosphate | - |
? | |
D-Glyceraldehyde 3-phosphate | - |
Trypanosoma cruzi | Glycerone phosphate | - |
? | |
D-Glyceraldehyde 3-phosphate | - |
Leishmania mexicana | Glycerone phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Trypanosoma brucei |
dimer | - |
Leishmania mexicana |
dimer | 2 * 27244, calculation from nucleotide sequence | Trypanosoma cruzi |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8.5 | - |
Trypanosoma brucei |
7 | 8.5 | - |
Trypanosoma cruzi |
7 | 8.5 | - |
Leishmania mexicana |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 9 | pH 6.0: about 60% of maximal activity, pH 9.0: about 50% of maximal activity | Trypanosoma brucei |
6 | 9 | pH 6.0: about 60% of maximal activity, pH 9.0: about 50% of maximal activity | Trypanosoma cruzi |
6 | 9 | pH 6.0: about 60% of maximal activity, pH 9.0: about 50% of maximal activity | Leishmania mexicana |