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Literature summary for 5.2.1.8 extracted from

  • Rathbun, K.; Hall, J.; Thompson, S.
    Cj0596 is a periplasmic peptidyl prolyl cis-trans isomerase involved in Campylobacter jejuni motility, invasion, and colonization (2009), BMC Microbiol., 9, 160.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene cj0596, expression of His-tagged Cj0596 protein in Escherichia coli strain BL21(DE3). Quantitative real-time reverse transcription PCR expression analysis of wild-type enzyme and revertant mutant, overview Campylobacter jejuni

Protein Variants

Protein Variants Comment Organism
additional information construction of a cj0596 deletion mutant derivative of strain 81-176, isolation of a revertant of this mutant by restoring the gene to its original chromosomal location using streptomycin counterselection. The cj0596 mutant strain demonstrates a slightly decreased growth rate and lower final growth yield, yet it is more motile and more invasive of human intestinal epithelial cells than wild-type, phenotype, overview Campylobacter jejuni

Localization

Localization Comment Organism GeneOntology No. Textmining
periplasm
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Campylobacter jejuni
-
-

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
gene cj0596
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Campylobacter jejuni 81-176
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gene cj0596
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information expression of cj0596 is slightly higher at 37°C than at 42°C Campylobacter jejuni
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information Cj0596 has PPIase activity, cleavage of N-Suc-Ala-Ala-Pro-Phe-4-nitroanilide Campylobacter jejuni ?
-
?
additional information Cj0596 has PPIase activity, cleavage of N-Suc-Ala-Ala-Pro-Phe-4-nitroanilide Campylobacter jejuni 81-176 ?
-
?

Synonyms

Synonyms Comment Organism
Cj0596
-
Campylobacter jejuni
peptidyl prolyl cis-trans isomerase
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Campylobacter jejuni

General Information

General Information Comment Organism
physiological function Cj0596 plays a role in interaction with host cells. Cj0596 is a periplasmic peptidyl prolyl cis-trans isomerase involved in Campylobacter jejuni motility, invasion, and colonization Campylobacter jejuni