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Literature summary for 5.2.1.8 extracted from

  • Obama, K.; Kato, T.; Hasegawa, S.; Satoh, S.; Nakamura, Y.; Furukawa, Y.
    Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells (2006), Clin. Cancer Res., 12, 70-76.
    View publication on PubMed

Application

Application Comment Organism
medicine enzyme isoform PPIL1 is frequently overexpressed in colon cancer cells. Wild-type PPIL1 shows a growth-promoting effect on NIH-3T3 and HEK-293 cells. Consistently, transfection with its siRNA reduces gene expression and retards growth of colon cancer cells. Enzyme interacts with SNW1/SKI-binding protein and with stathmin Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
isoform PPIL1
-

Source Tissue

Source Tissue Comment Organism Textmining
carcinoma cell
-
Homo sapiens
-
colon
-
Homo sapiens
-

Subunits

Subunits Comment Organism
More enzyme interacts with SNW1/SKI-binding protein and with stathmin Homo sapiens

Synonyms

Synonyms Comment Organism
PPIL1
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Homo sapiens