Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.2.1.8 extracted from

  • Hermans, P.W.; Adrian, P.V.; Albert, C.; Estevao, S.; Hoogenboezem, T.; Luijendijk, I.H.; Kamphausen, T.; Hammerschmidt, S.
    The Streptococcal lipoprotein rotamase A (SlrA) is a functional peptidyl-prolyl isomerase involved in pneumococcal colonization (2006), J. Biol. Chem., 281, 968-976.
    View publication on PubMed
Search for more literature for 5.2.1.8

Protein Variants

Protein Variants Comment Organism
additional information enzyme knockout mutant, in mouse pneumonia model no significant difference to wild-type. Deficiency in enzyme does not reduce binding activity of strain to host target proteins but results in enhanced uptake by professional phagocytes Streptococcus pneumoniae

Organism

Organism UniProt Comment Textmining
Streptococcus pneumoniae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinyl-Ala-Ala-(cis)-Pro-Phe-p-nitroanilide
-
 Streptococcus pneumoniae succinyl-Ala-Ala-(trans)-Pro-Phe-p-nitroanilide
-
 ?
succinyl-Ala-Gln-(cis)-Pro-Phe-p-nitroanilide 27% of the activity with succinyl-Ala-Ala-(cis)-Pro-Phe-p-nitroanilide Streptococcus pneumoniae succinyl-Ala-Gln-(trans)-Pro-Phe-p-nitroanilide
-
 ?
succinyl-Ala-Glu-(cis)-Pro-Phe-p-nitroanilide 13% of the activity with succinyl-Ala-Ala-(cis)-Pro-Phe-p-nitroanilide Streptococcus pneumoniae succinyl-Ala-Glu-(trans)-Pro-Phe-p-nitroanilide
-
 ?
succinyl-Ala-Gly-(cis)-Pro-Phe-p-nitroanilide 37% of the activity with succinyl-Ala-Ala-(cis)-Pro-Phe-p-nitroanilide Streptococcus pneumoniae succinyl-Ala-Gly-(trans)-Pro-Phe-p-nitroanilide
-
 ?
succinyl-Ala-Leu-(cis)-Pro-Phe-p-nitroanilide 67% of the activity with succinyl-Ala-Ala-(cis)-Pro-Phe-p-nitroanilide Streptococcus pneumoniae succinyl-Ala-Leu-(trans)-Pro-Phe-p-nitroanilide
-
 ?
succinyl-Ala-Phe-(cis)-Pro-Phe-p-nitroanilide 35% of the activity with succinyl-Ala-Ala-(cis)-Pro-Phe-p-nitroanilide Streptococcus pneumoniae succinyl-Ala-Phe-(trans)-Pro-Phe-p-nitroanilide
-
 ?
succinyl-Ala-Val-(cis)-Pro-Phe-p-nitroanilide 76% of the activity with succinyl-Ala-Ala-(cis)-Pro-Phe-p-nitroanilide Streptococcus pneumoniae succinyl-Ala-Val-(trans)-Pro-Phe-p-nitroanilide
-
 ?

Synonyms

Synonyms Comment Organism
SlrA
-
 Streptococcus pneumoniae