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Literature summary for 5.2.1.4 extracted from

  • Liu, K.; Xu, Y.; Zhou, N.Y.
    Identification of a specific maleate hydratase in the direct hydrolysis route of the gentisate pathway (2015), Appl. Environ. Microbiol., 81, 5753-5760 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.2.1.4

Activating Compound

Activating Compound Comment Organism Structure
glutathione dependent on glutathione Pseudomonas alcaligenes

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli Pseudomonas alcaligenes

Organism

Organism UniProt Comment Textmining
Pseudomonas alcaligenes
-
-
-
Pseudomonas alcaligenes NCIMB 9867
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pseudomonas alcaligenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-Maleylpyruvate
-
 Pseudomonas alcaligenes 3-Fumarylpyruvate
-
 r
3-Maleylpyruvate
-
 Pseudomonas alcaligenes NCIMB 9867 3-Fumarylpyruvate
-
 r

Synonyms

Synonyms Comment Organism
HbzG
-
 Pseudomonas alcaligenes

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
23
-
 assay at Pseudomonas alcaligenes

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Pseudomonas alcaligenes

General Information

General Information Comment Organism
malfunction disruption of hbzG eliminates the ability to grow on gentisate Pseudomonas alcaligenes
metabolism the enzyme is involved in maleylpyruvate catabolism in the gentisate pathway. The maleylpyruvate isomerization route is a complete pathway for gentisate catabolism in the mutant strain strain SponMu, whereas the direct hydrolysis route is not Pseudomonas alcaligenes