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Literature summary for 5.2.1.2 extracted from
- Phenylalanine-induced leucopenia in genetic and dichloroacetic acid generated deficiency of glutathione transferase Zeta (2009), Biochem. Pharmacol., 77, 1358-1363.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Dichloroacetic acid | DCA | Mus musculus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-maleylacetoacetate | Mus musculus | - |
4-fumarylacetoacetate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-maleylacetoacetate | - |
Mus musculus | 4-fumarylacetoacetate | - |
? | |
| chlorofluoroacetic acid + ? | activity assay | Mus musculus | glyoxylate + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| maleylacetoacetate isomerase | bifunctional enzyme EC 2.5.1.18, glutathione transferase Zeta, GSTZ1-1 | Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | catalyses a significant step in the catabolism of phenylalanine and tyrosine | Mus musculus |
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Release 2023.1 (January 2023)
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