Application | Comment | Organism |
---|---|---|
synthesis | recombinant methylmalonyl-CoA epimerase enables biocatalytic epimerisation of C-2 methyl- and ethylmalonyl-CoA. When coupled with variant carboxymethylproline synthase CarB and crotonyl-CoA carboxylase reductase, the methylmalonyl-CoA epimerase forms part of a three-enzyme, one-pot procedure for the production of functionalised C-5 carboxyalkylprolines from crotonyl-CoA, carbon dioxide and L-glutamate semialdehyde/5-hydroxyproline/pyrroline-5-carboxylate | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q96PE7 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2R)-methylmalonyl-CoA | - |
Homo sapiens | (2S)-methylmalonyl-CoA | - |
? | |
(2S)-ethylmalonyl-CoA | - |
Homo sapiens | (2R)-ethylmalonyl-CoA | - |
? |