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Literature summary for 5.1.99.1 extracted from

  • Fuller, J.Q.; Leadlay, P.F.
    Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii (1983), Biochem. J., 213, 643-650.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.1.99.1

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Propionibacterium freudenreichii subsp. shermanii
-
-
-

Reaction

Reaction Comment Organism Reaction ID
(R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA with (2R)-methylmalonyl-CoA as substrate: two enzyme bases act respectively as proton donor and acceptor, the release of product is slow, and the reprotonation step on the enzyme is reversible, without leading to isotopic exchange with the solvent Propionibacterium freudenreichii subsp. shermanii
a

Source Tissue

Source Tissue Comment Organism Textmining
leukocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-2-Methyl-3-oxopropanoyl-CoA
-
 Homo sapiens (S)-2-Methyl-3-oxopropanoyl-CoA
-
 ?
(R)-2-Methyl-3-oxopropanoyl-CoA
-
 Propionibacterium freudenreichii subsp. shermanii (S)-2-Methyl-3-oxopropanoyl-CoA
-
 ?