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Literature summary for 5.1.3.19 extracted from

  • Habicher, J.; Haitina, T.; Eriksson, I.; Holmborn, K.; Dierker, T.; Ahlberg, P.E.; Ledin, J.
    Chondroitin / dermatan sulfate modification enzymes in zebrafish development (2015), PLoS ONE, 10, e0121957 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene dse, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis Danio rerio
gene dsela, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis Danio rerio
gene dselb, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis Danio rerio

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Chondroitin D-glucuronate Danio rerio
-
Dermatan L-iduronate
-
r

Organism

Organism UniProt Comment Textmining
Danio rerio
-
-
-
Danio rerio B8A5U5
-
-
Danio rerio Q5RGL8
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Danio rerio
-
larva
-
Danio rerio
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Chondroitin D-glucuronate
-
Danio rerio Dermatan L-iduronate
-
r

Synonyms

Synonyms Comment Organism
dermatan sulfate epimerase
-
Danio rerio
dermatan sulfate epimerase-like a
-
Danio rerio
dermatan sulfate epimerase-like b
-
Danio rerio
DS-epi1
-
Danio rerio
DS-epi2
-
Danio rerio
DSE
-
Danio rerio
DSEL
-
Danio rerio
dsela
-
Danio rerio
dselb
-
Danio rerio

General Information

General Information Comment Organism
evolution conversion of GlcA residues into the stereoisomer IdoA is mediated by two dermatan sulfate epimerases, DSE (DS-epi1) and DSEL (DS-epi2) Danio rerio
metabolism the enzyme is involved in the chondroitin/dermatan sulfate biosynthesis, overview Danio rerio
physiological function conversion of GlcA residues into the stereoisomer IdoA is mediated by two dermatan sulfate epimerases, DSE (DS-epi1) and DSEL (DS-epi2), modification reactions in chondroitin/dermatan sulfate biosynthesis, overview Danio rerio