Literature summary for 5.1.3.14 extracted from

Ghaderi, D.; Strauss, H.M.; Reinke, S.; Cirak, S.; Reutter, W.; Lucka, L.; Hinderlich, S.
Evidence for dynamic interplay of different oligomeric states of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase by biophysical methods (2007), J. Mol. Biol., 369, 746-758.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in insect cells	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
CMP-Neu5Ac	allosterical feed-back-inhibition	Rattus norvegicus
UDP	competitive inhibition	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
330000	-	dynamic light-scattering	Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
UDP-GlcNAc + H2O	Rattus norvegicus	biosynthesis of sialic acids	ManNAc + UDP	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-GlcNAc + H2O	biosynthesis of sialic acids	Rattus norvegicus	ManNAc + UDP	-	?

Synonyms

Synonyms	Comment	Organism
His-rGNE	-	Rattus norvegicus
UDP-N-acetylglucosamine 2-epimerase	-	Rattus norvegicus

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Release 2023.1 (January 2023)