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Literature summary for 5.1.1.7 extracted from
- Enzymology of bacterial lysine biosynthesis (1998), Adv. Enzymol. Relat. Areas Mol. Biol., 72, 279-324.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| thiol compound | required for activity | Escherichia coli |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-(4-amino-4-carboxybutyl)aziridine-2-carboxylic acid | irreversible | Escherichia coli | |
| iodoacetamide | - |
Escherichia coli | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.16 | - |
LL-diaminoheptanedioate | - |
Escherichia coli | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 34000 | - |
1 * 34000, SDS-PAGE | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 34000, SDS-PAGE | Escherichia coli |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 67 | - |
meso-diaminoheptanedioate | - |
Escherichia coli | |
| 84 | - |
LL-diaminoheptanedioate | - |
Escherichia coli | |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
rapid loss of activity when stored in absence of dithiothreitol | Escherichia coli |
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