Any feedback?
Literature summary for 5.1.1.18 extracted from
- Role of serine racemase in behavioral sensitization in mice after repeated administration of methamphetamine (2012), PLoS ONE, 7, e35494.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SRR | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | repeated administration of methamphetamine results in behavioral sensitization in wild-type, but not in knockout mutant Srr-KO mice, while METH-induced acute hyperlocomotion is similar in wild-type and mutant mice. Pretreatment with D-serine does not affect the development of behavioral sensitization after repeated methamphetamine administration | Mus musculus |
| physiological function | serine racemase is an enzyme which synthesizes D-serine, an endogenous co-agonist of N-methyl-D-aspartate (NMDA) receptors. N-methyl-D-aspartate receptors play a role in behavioral abnormalities observed after administration of the psychostimulant, methamphetamine. Role of serine racemase in behavioral sensitization in mice after repeated administration of methamphetamine, overview | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
