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Literature summary for 5.1.1.18 extracted from
- Serine racemase suppresses chondrogenic differentiation in cartilage in a Sox9-dependent manner (2008), J. Cell. Physiol., 215, 320-328.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpression in ATDC5 cell and in COS7 cell | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | serine racemase may negatively regulate cellular differentiation through the inhibition of sry-typeHMGbox 9, i.e.Sox9 transcriptional activity in chondrocytes | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| chondrocyte | mRNA is ubiquitously expressed in all cell layers of proliferating to hypertrophic chondrocytes | Rattus norvegicus | - |
| tibia | of neonatal rat, mRNA is ubiquitously expressed in all cell layers of proliferating to hypertrophic chondrocytes | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | serine racemase may negatively regulate cellular differentiation through the inhibition of sry-typeHMGbox 9, i.e.Sox9 transcriptional activity in chondrocytes | Rattus norvegicus | ? | - |
? | |
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Release 2023.1 (January 2023)
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