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Literature summary for 5.1.1.1 extracted from

  • Wei, Y.; Qiu, W.; Zhou, X.D.; Zheng, X.; Zhang, K.K.; Wang, S.D.; Li, Y.Q.; Cheng, L.; Li, J.Y.; Xu, X.; Li, M.Y.
    Alanine racemase is essential for the growth and interspecies competitiveness of Streptococcus mutans (2016), Int. J. Oral Sci., 8, 231-238 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information construction of an alr mutant strain. D-Ala starvation causes cell morphology alterations of the alr mutant Streptococcus mutans serotype c

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-alanine Streptococcus mutans serotype c
-
D-alanine
-
r
L-alanine Streptococcus mutans serotype c ATCC 700610 / UA159
-
D-alanine
-
r

Organism

Organism UniProt Comment Textmining
Streptococcus mutans serotype c Q8DSF4
-
-
Streptococcus mutans serotype c ATCC 700610 / UA159 Q8DSF4
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-alanine
-
Streptococcus mutans serotype c D-alanine
-
r
L-alanine
-
Streptococcus mutans serotype c ATCC 700610 / UA159 D-alanine
-
r

Synonyms

Synonyms Comment Organism
ALR
-
Streptococcus mutans serotype c

General Information

General Information Comment Organism
malfunction depletion of alr in Streptococcus mutans significantly compromises its competitiveness with other co-residents, e.g. Streptococcus sanguinis, in the oral biofilm. D-Ala starvation causes cell morphology alterations of the alr mutant Streptococcus mutans serotype c
physiological function the enzyme is an essential factor to maintain the growth and cell wall integrity of Streptococcus mutans Streptococcus mutans serotype c