Cloned (Comment) | Organism |
---|---|
cloned and overexpressed | Salmonella enterica subsp. enterica serovar Typhimurium |
Crystallization (Comment) | Organism |
---|---|
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
sirohydrochlorin + Co2+ | Priestia megaterium | cobalamin biosynthesis | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | Clostridium acetobutylicum | cobalamin biosynthesis | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | Porphyromonas gingivalis | cobalamin biosynthesis | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | Clostridioides difficile | cobalamin biosynthesis | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | Cereibacter sphaeroides | cobalamin biosynthesis, oxygen-independent pathway | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | Pseudomonas aeruginosa | cobalamin biosynthesis, oxygen-independent pathway | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | Salmonella enterica subsp. enterica serovar Typhimurium | cobalamin biosynthesis, oxygen-independent route, CbiK is a biglobal enzyme containing 2 a/b domains, which generate an active site with a deep rectangular cleft at their interface | cobaltsirohydrochlorin + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cereibacter sphaeroides | - |
- |
- |
Clostridioides difficile | - |
- |
- |
Clostridium acetobutylicum | - |
- |
- |
no activity in Bacillus subtilis | - |
- |
- |
no activity in eukaryota | - |
- |
- |
Porphyromonas gingivalis | - |
- |
- |
Priestia megaterium | - |
- |
- |
Pseudomonas aeruginosa | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Oxidation Stability | Organism |
---|---|
requires molecular oxygen | Pseudomonas aeruginosa |
Purification (Comment) | Organism |
---|---|
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | CbiK fused together with CbiL as a multifunctional protein | Clostridioides difficile | ? | - |
? | |
precorrin-2 + Co2+ | - |
Pseudomonas aeruginosa | Co-precorrin-2 + H+ | - |
? | |
sirohydrochlorin + Co2+ | - |
Salmonella enterica subsp. enterica serovar Typhimurium | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | - |
Cereibacter sphaeroides | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | - |
Priestia megaterium | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | - |
Pseudomonas aeruginosa | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | - |
Clostridium acetobutylicum | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | - |
Porphyromonas gingivalis | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | - |
Clostridioides difficile | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | cobalamin biosynthesis | Priestia megaterium | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | cobalamin biosynthesis | Clostridium acetobutylicum | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | cobalamin biosynthesis | Porphyromonas gingivalis | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | cobalamin biosynthesis | Clostridioides difficile | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | cobalamin biosynthesis, oxygen-independent pathway | Cereibacter sphaeroides | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | cobalamin biosynthesis, oxygen-independent pathway | Pseudomonas aeruginosa | cobaltsirohydrochlorin + H+ | - |
? | |
sirohydrochlorin + Co2+ | cobalamin biosynthesis, oxygen-independent route, CbiK is a biglobal enzyme containing 2 a/b domains, which generate an active site with a deep rectangular cleft at their interface | Salmonella enterica subsp. enterica serovar Typhimurium | cobaltsirohydrochlorin + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CbiK | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
CbiK | - |
Cereibacter sphaeroides |
CbiK | - |
Priestia megaterium |
CbiK | - |
Pseudomonas aeruginosa |
CbiK | - |
Clostridium acetobutylicum |
CbiK | - |
Porphyromonas gingivalis |
CbiK | - |
Clostridioides difficile |
cobalt chelatase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
cobalt chelatase | - |
Cereibacter sphaeroides |
cobalt chelatase | - |
Priestia megaterium |
cobalt chelatase | - |
Pseudomonas aeruginosa |
cobalt chelatase | - |
Clostridium acetobutylicum |
cobalt chelatase | - |
Porphyromonas gingivalis |
cobalt chelatase | - |
Clostridioides difficile |