Literature summary for 4.98.1.1 extracted from

Wong, K.F.; Ho, J.W.
Identification of histidine-60 interaction with copper in activation of Chironomidae ferrochelatase (2006), Protein Pept. Lett., 13, 443-446.

Protein Variants

Protein Variants	Comment	Organism
H60D	2fold increased activity	Chironomidae
H60N	more than 4fold increased activity	Chironomidae

Metals/Ions	Comment	Organism	Structure
Cu2+	binding interaction of copper with histidine-60, the highly conserved H60 is a key molecular determinant in directing a catalytically competent mode of metal binding in the active site	Chironomidae

Organism	UniProt	Comment	Textmining
Chironomidae	-	-	-

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Release 2023.1 (January 2023)