BRENDA - Enzyme Database
show all sequences of 4.6.1.6

Interaction of rat brain cytidylate cyclase with phospholipids

Mori, S.; Muto, N.; Yamamoto, I.; Biochem. Biophys. Res. Commun. 162, 1502-1507 (1989)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
L-alpha-phosphatidylcholine
-
Rattus norvegicus
Inhibitors
Inhibitors
Commentary
Organism
Structure
deoxycholate
-
Rattus norvegicus
L-alpha-Phosphatidic acid
-
Rattus norvegicus
L-alpha-Phosphatidylethanolamine
-
Rattus norvegicus
L-alpha-Phosphatidylserine
-
Rattus norvegicus
additional information
no inhibition with L-alpha-phosphatidylcholine
Rattus norvegicus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
membrane-bound
Rattus norvegicus
16020
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
CTP
Rattus norvegicus
-
3',5'-cyclic CMP + diphosphate
-
-
?
CTP
Rattus norvegicus Wistar
-
3',5'-cyclic CMP + diphosphate
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
; rat
-
Rattus norvegicus Wistar
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
-
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
CTP
-
648788
Rattus norvegicus
3',5'-cyclic CMP + diphosphate
-
-
-
?
CTP
-
648788
Rattus norvegicus Wistar
3',5'-cyclic CMP + diphosphate
-
-
-
?
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
L-alpha-phosphatidylcholine
-
Rattus norvegicus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
deoxycholate
-
Rattus norvegicus
L-alpha-Phosphatidic acid
-
Rattus norvegicus
L-alpha-Phosphatidylethanolamine
-
Rattus norvegicus
L-alpha-Phosphatidylserine
-
Rattus norvegicus
additional information
no inhibition with L-alpha-phosphatidylcholine
Rattus norvegicus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
membrane-bound
Rattus norvegicus
16020
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
CTP
Rattus norvegicus
-
3',5'-cyclic CMP + diphosphate
-
-
?
CTP
Rattus norvegicus Wistar
-
3',5'-cyclic CMP + diphosphate
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
CTP
-
648788
Rattus norvegicus
3',5'-cyclic CMP + diphosphate
-
-
-
?
CTP
-
648788
Rattus norvegicus Wistar
3',5'-cyclic CMP + diphosphate
-
-
-
?
Other publictions for EC 4.6.1.6
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
714199
Goettle
Cytidylyl and uridylyl cyclase ...
Bacillus anthracis, Bordetella pertussis
Biochemistry
49
5494-5503
2010
-
-
-
-
-
-
12
3
-
2
-
-
-
5
-
-
-
-
-
-
-
-
2
-
-
-
-
3
-
-
-
-
13
-
-
-
-
-
-
-
-
-
-
12
13
3
-
2
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
3
-
-
-
-
-
-
-
-
3
3
648792
Newton
Estimation of cytidylyl cyclas ...
Rattus norvegicus, Rattus norvegicus Lister Hooded
Rapid Commun. Mass. Spectrom.
11
189-194
1997
-
-
-
-
-
-
-
-
1
-
-
2
-
3
-
-
-
-
-
3
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
3
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
648791
Muto
Cytidylate cyclase activity is ...
Rattus norvegicus
Life Sci.
52
13-20
1993
1
-
-
-
-
-
-
-
1
-
-
1
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
648789
Mori
Characterization of detergent ...
Rattus norvegicus
Second Messengers Phosphoproteins
13
1-12
1990
-
-
-
-
-
-
2
1
1
2
-
1
-
2
-
-
-
-
-
2
-
-
2
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
1
2
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
648790
Newton
Cytidylate cyclase: developmen ...
Rattus norvegicus
Biochem. J.
265
581-586
1990
-
-
-
-
-
-
-
1
-
2
-
1
-
3
-
-
-
-
-
9
1
-
1
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
1
-
-
-
-
-
9
1
-
1
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
648788
Mori
Interaction of rat brain cytid ...
Rattus norvegicus, Rattus norvegicus Wistar
Biochem. Biophys. Res. Commun.
162
1502-1507
1989
1
-
-
-
-
-
5
-
1
-
-
2
-
167
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
5
-
-
1
-
-
2
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
648786
Newton
Extraction, purification, iden ...
Rattus norvegicus
Biochem. J.
236
431-439
1986
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
648787
Newton
-
Identification of the products ...
Rattus norvegicus
Biochem. Soc. Trans.
14
964-965
1986
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
648785
Newton
-
3',5'-cyclic UMP, -cyclic IMP, ...
Rattus norvegicus, Rattus norvegicus Lister Hooded
Biochem. Soc. Trans.
13
1134-1135
1985
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
648784
Cech
Cytidine 3,5-monophosphate (cy ...
Mus musculus
Biochem. Biophys. Res. Commun.
80
119-125
1978
-
-
-
-
-
-
2
1
-
2
-
1
-
1
-
-
-
-
-
1
-
-
1
-
1
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
2
-
1
-
-
-
-
-
1
-
-
1
-
1
1
-
-
1
1
-
-
-
-
-
-
-
-