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Literature summary for 4.6.1.20 extracted from

  • Nabavi, S.; Nazar, R.N.
    Cleavage-induced termination in U2 snRNA gene expression (2010), Biochem. Biophys. Res. Commun., 393, 461-465.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
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Schizosaccharomyces pombe GP969
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General Information

General Information Comment Organism
physiological function the endonuclease cleavage of many small nuclear RNAs is equally important in terminating the transcription of the U2 snRNA in Schizosaccharomyces pombe. Reversed torpedoes model for the termination and maturation of the U2 snRNA, the Pac1 endonuclease cleavage provides entry sites for the 3' and 5' exonuclease activities, leading to RNA maturation in one direction and transcript termination in the other Schizosaccharomyces pombe