Literature summary for 4.6.1.2 extracted from

Tanwar, M.; Sharma, K.; Moar, P.; Kateriya, S.
Biochemical characterization of the engineered soluble photoactivated guanylate cyclases from microbes expands optogenetic tools (2018), Appl. Biochem. Biotechnol., 185, 1014-1028 .

Search for more literature for 4.6.1.2

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Naegleria gruberi
expression in Escherichia coli	Turneriella parva

Protein Variants

Protein Variants	Comment	Organism
K196E/D264K/T266G	engineering of photoactivated adenylyl cyclase to photoactivated guanylyl cyclase, via mutagenesis of the substrate binding-specific residues in cyclase homology domain. The mutant shows typical BLUF photoreceptor properties	Turneriella parva
K237E/D306K/T308G	isoform PAC2, engineering of photoactivated adenylyl cyclase to photoactivated guanylyl cyclase, via mutagenesis of the substrate binding-specific residues in cyclase homology domain. The mutant shows typical BLUF photoreceptor properties	Naegleria gruberi
K332E/D400K/T402G	isoform PAC3, engineering of photoactivated adenylyl cyclase to photoactivated guanylyl cyclase, via mutagenesis of the substrate binding-specific residues in cyclase homology domain. The mutant shows typical BLUF photoreceptor properties	Naegleria gruberi

Organism

Organism	UniProt	Comment	Textmining
Naegleria gruberi	-	-	-
Turneriella parva	-	-	-
Turneriella parva DSM 21527	-	-	-

Synonyms

Synonyms	Comment	Organism
Pac2	-	Naegleria gruberi
Pac3	-	Naegleria gruberi

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)