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Literature summary for 4.6.1.2 extracted from

  • Hidaka, A.; Azuma, Y.T.; Nakajima, H.; Takeuchi, T.
    Nitric oxide and carbon monoxide act as inhibitory neurotransmitters in the longitudinal muscle of C57BL/6J mouse distal colon (2010), J. Pharmacol. Sci., 112, 231-241.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
carbon monoxide
-
Mus musculus
nitric oxide
-
Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one a soluble guanylate cyclase inhibitor, maximal inhibition (70%) at 0.01 mM Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP Mus musculus
-
3',5'-cyclic-GMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastrointestinal smooth muscle
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
Mus musculus 3',5'-cyclic-GMP + diphosphate
-
?

Synonyms

Synonyms Comment Organism
sGC
-
Mus musculus
soluble guanylyl cyclase
-
Mus musculus