Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NO | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1H-[1,2,4]oxadiazolo [4,3,-a]quinoxalin-1-one | i.e. ODQ, in vivo treatment with the sGC inhibitors ODQ does not decrease plasmatic and jejunal cGMP levels, nor does it influence the change in electrical field-induced relaxation; i.e. ODQ, in vivo treatment with the sGC inhibitors ODQ does not decrease plasmatic and jejunal cGMP levels, nor does it influence the change in electrical field-induced relaxation | Rattus norvegicus | |
methylene blue | in vivo treatment with the sGC inhibitor methylene blue does not decrease plasmatic and jejunal cGMP levels, nor does it influence the change in electrical filed stimulation-induced relaxation; in vivo treatment with the sGC inhibitor methylene blue does not decrease plasmatic and jejunal cGMP levels, nor does it influence the change in electrical filed stimulation-induced relaxation | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | Rattus norvegicus | role of soluble guanylate cyclase during the inflammatory phase of postoperative illius, overview | 3',5'-cyclic GMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q02108 | male Wistar-Han rats | - |
Rattus norvegicus | Q02153 | beta-subunit; male Wistar-Han rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
ileum | - |
Rattus norvegicus | - |
intestine | - |
Rattus norvegicus | - |
jejunum | - |
Rattus norvegicus | - |
smooth muscle | gastrointestinal | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | - |
Rattus norvegicus | 3',5'-cyclic GMP + diphosphate | - |
? | |
GTP | role of soluble guanylate cyclase during the inflammatory phase of postoperative illius, overview | Rattus norvegicus | 3',5'-cyclic GMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
sGC | - |
Rattus norvegicus |
soluble guanylate cyclase | - |
Rattus norvegicus |