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Literature summary for 4.6.1.2 extracted from

  • Stasch, J.P.; Hobbs, A.J.
    NO-independent, haem-dependent soluble guanylate cyclase stimulators (2009), Handb. Exp. Pharmacol., 191, 277-308.
    View publication on PubMed
Search for more literature for 4.6.1.2

Activating Compound

Activating Compound Comment Organism Structure
BAY 41-2272 stimulator of the NO-independent, heme-dependent soluble guanylate cyclase, acts independently of and in synergism with NO producing anti-aggregatory, anti-proliferative, and vasodilatory effects, overview Homo sapiens
BAY 41-8543 stimulator of the NO-independent, heme-dependent soluble guanylate cyclase, acts independently of and in synergism with NO producing anti-aggregatory, anti-proliferative, and vasodilatory effects, overview Homo sapiens
BaY 63-2521 stimulator of the NO-independent, heme-dependent soluble guanylate cyclase, acts independently of and in synergism with NO producing anti-aggregatory, anti-proliferative, and vasodilatory effects, overview Homo sapiens
CFM-1571 stimulator of the NO-independent, heme-dependent soluble guanylate cyclase, acts independently of and in synergism with NO producing anti-aggregatory, anti-proliferative, and vasodilatory effects, overview Homo sapiens
additional information identification of stimulating acryl-amide compounds, that act independently of YC-1 stimulators and promote smooth muscle relaxation Homo sapiens
YC-1 stimulator of the NO-independent, heme-dependent soluble guanylate cyclase, acts independently of and in synergism with NO producing anti-aggregatory, anti-proliferative, and vasodilatory effects, overview Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
additional information NO-independent, heme-dependent soluble guanylate cyclase Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP Homo sapiens the NO-independent, heme-dependent soluble guanylate cyclase acts as an NO receptor 3',5'-cyclic GMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
 Homo sapiens 3',5'-cyclic GMP + diphosphate
-
 ?
GTP the NO-independent, heme-dependent soluble guanylate cyclase acts as an NO receptor Homo sapiens 3',5'-cyclic GMP + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
NO-independent, heme-dependent soluble guanylate cyclase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
heme NO-independent, heme-dependent soluble guanylate cyclase Homo sapiens