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Literature summary for 4.6.1.2 extracted from
- Distribution of soluble guanylyl cyclase in rat retina (2007), J. Comp. Neurol., 502, 734-745.
Application
| Application | Comment | Organism |
|---|---|---|
| additional information | NO-cGMP pathway modulates the neural circuitry in inner retina, preferentially within the cone pathway | Rattus norvegicus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 70000 | - |
immunostaining | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
adult male Sprague-Dawley rats | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cerebellum | present at weaker levels | Rattus norvegicus | - |
| additional information | in cortex present at weaker levels, whereas photoreceptors, horizontal cells, Müller cells, and AII amacrine cells are immunonegative | Rattus norvegicus | - |
| retina | present at high levels in inner retina but barely detectable in outer retina, ganglion cells exhibit moderate staining for sGC, strong immunostaining in subpopulations of bipolar and amacrine cells, weak staining in rod bipolar cells | Rattus norvegicus | - |
| spinal cord | present at weaker levels | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP | - |
Rattus norvegicus | 3',5'-cyclic GMP + diphosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| sGC | - |
Rattus norvegicus |
| soluble guanylate cyclase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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