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Literature summary for 4.6.1.2 extracted from
- Functional properties of a naturally occurring isoform of soluble guanylyl cyclase (1998), Biochem. J., 335, 125-130.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| CO | activation | Homo sapiens |  |
| NO | activation | Homo sapiens | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of isoform alpha2,beta1 in Sf9 cells | Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.09 | - |
GTP | - |
Homo sapiens | |
| 0.1 | - |
GTP | alpha2,beta1 isoform | Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| soluble | - |
Homo sapiens | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 70000 | - |
alpha,beta 1 * 73000 + 1 * 70000, SDS-PAGE, soluble form | Homo sapiens |
| 73000 | - |
alpha,beta 1 * 73000 + 1 * 70000, SDS-PAGE, soluble form | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P33402 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| placenta | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP | GTP in form of MgGTP2- | Homo sapiens | 3',5'-cyclic GMP + diphosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | alpha,beta 1 * 73000 + 1 * 70000, SDS-PAGE, soluble form | Homo sapiens |
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