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Literature summary for 4.6.1.18 extracted from
- Bactericidal activity engineered on human pancreatic ribonuclease and onconase (2009), Mol. Pharm., 6, 531-542.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Homo sapiens |
- |
Lithobates pipiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| R4A/K6A/Q9E/D16G/S17N/T36Y/Q37R/G38W | 29.6% catalytic efficiency of wild type | Homo sapiens |
| T25R/N26W/L27R | 8.4% catalytic efficiency of wild type | Lithobates pipiens |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 11990 | - |
mutant T25R/N26W/L27R analyzed by MALDI-TOF mass spectrometry | Lithobates pipiens |
| 14750 | - |
mutant R4A/K6A/Q9E/D16G/S17N/T36Y/Q37R/G38W analyzed by MALDI-TOF mass spectrometry | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Lithobates pipiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Renatured (Commentary)
| Renatured (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| onconase | - |
Lithobates pipiens |
| pancreatic ribonuclease | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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