Literature summary for 4.6.1.18 extracted from

Ghosh, K.S.; Maiti, T.K.; Debnath, J.; Dasgupta, S.
Inhibition of ribonuclease A by polyphenols present in green tea (2007), Proteins, 69, 566-580.

Search for more literature for 4.6.1.18

Inhibitors

Inhibitors	Comment	Organism	Structure
epicatechin	0.04 mM, 4.4% inhibition, noncompetitve, CD spectral analysis of complex with enzyme, preferred site of binding is around residues 34-39 with possible hydrogen bonding to K7 and R10	Bos taurus
epicatechin gallate	0.04 mM, 12.7% inhibition, noncompetitve, CD spectral analysis of complex with enzyme, preferred site of binding is around residues 34-39 with possible hydrogen bonding to K7 and R10	Bos taurus
epigallocatechin	0.04 mM, 6.9% inhibition, noncompetitve, CD spectral analysis of complex with enzyme, preferred site of binding is around residues 34-39 with possible hydrogen bonding to K7 and R10	Bos taurus
epigallocatechin gallate	0.04 mM, 18.4% inhibition, noncompetitve, CD spectral analysis of complex with enzyme, preferred site of binding is around residues 34-39 with possible hydrogen bonding to K7 and R10	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	P61823	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
pancreas	-	Bos taurus	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)