Literature summary for 4.6.1.18 extracted from

Shehi, E.; Serina, S.; Fumagalli, G.; Vanoni, M.; Consonni, R.; Zetta, L.; Deho, G.; Tortora, P.; Fusi, P.
The Sso7d DNA-binding protein from Sulfolobus solfataricus has ribonuclease activity. (2001), FEBS Lett., 497, 131-136.

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Protein Variants

Protein Variants	Comment	Organism
E35L	complete loss of ribonuclease activity	Saccharolobus solfataricus
K12L	complete loss of ribonuclease activity	Saccharolobus solfataricus

Organism

Organism	UniProt	Comment	Textmining
Saccharolobus solfataricus	-	ribonuclease activity of Sso7d DNA-binding protein	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
RNA + H2O	enzyme attacks both predicted double- and single-stranded RNA stretches, with no evident preference for specific sequences or individual bases	Saccharolobus solfataricus	3'-phosphomononucleotides + 3'-phosphooligonucleotides	-	?

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Release 2023.1 (January 2023)