Literature summary for 4.6.1.18 extracted from

Polydoridis, S.; Leonidas, D.D.; Oikonomakos, N.G.; Archontis, G.
Recognition of ribonuclease a by 3-5-pyrophosphate-linked dinucleotide inhibitors: a molecular dynamics/continuum electrostatics analysis (2007), Biophys. J., 92, 1659-1672.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
multi-ns molecular dynamics simulations of enzyme in complex with inhibitor 5'-phospho-2'-deoxyuridine-3-pyrophosphate (P-5)-adenosine-3-phosphate. The adenylate 5'-beta-phosphate binding position and the adenosine syn orientation constitute robust structural features in the complex	Bos taurus

Inhibitors

Inhibitors	Comment	Organism	Structure
5'-phospho-2'-deoxyuridine-3-diphosphate (P-5)-adenosine-3'-phosphate	i.e. pdUppA-3'-p, multi-ns molecular dynamics simulations of enzyme in complex with inhibitor	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	P61823	-	-

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Release 2023.1 (January 2023)