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Literature summary for 4.6.1.18 extracted from

  • Muskiet, F.A.J.; Welling, G.W.; Beintema, J.J.
    Studies on the primary structure of bison pancreatic ribonuclease (1976), Int. J. Pept. Protein Res., 8, 345-348.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RNA + H2O Bison bison endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA 3'-phosphomononucleotides + 3'-phosphooligonucleotides
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?

Organism

Organism UniProt Comment Textmining
Bison bison
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-
-

Purification (Commentary)

Purification (Comment) Organism
partial Bison bison

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclic 2',3'-nucleoside monophosphate + H2O second step of hydrolysis is irreversible Bison bison 3'-phosphomononucleotides
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ir
RNA + H2O endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA Bison bison 3'-phosphomononucleotides + 3'-phosphooligonucleotides
-
?
RNA + H2O first step of hydrolysis is reversible Bison bison cyclic 2',3'-nucleoside monophosphate
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r