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Literature summary for 4.6.1.18 extracted from

  • Van Dijk, H.; Sloots, B.; van der Berg, A.; Gaastra, W.; Beintema, J.J.
    The primary structure of muskrat pancreatic ribonuclease (1976), Int. J. Pept. Protein Res., 8, 305-316.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RNA + H2O Ondatra zibethicus endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA 3'-phosphomononucleotides + 3'-phosphooligonucleotides
-
?

Organism

Organism UniProt Comment Textmining
Ondatra zibethicus
-
muskrat
-

Purification (Commentary)

Purification (Comment) Organism
partial Ondatra zibethicus

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclic 2',3'-nucleoside monophosphate + H2O second step of hydrolysis is irreversible Ondatra zibethicus 3'-phosphomononucleotides
-
ir
RNA + H2O endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA Ondatra zibethicus 3'-phosphomononucleotides + 3'-phosphooligonucleotides
-
?
RNA + H2O first step of hydrolysis is reversible Ondatra zibethicus cyclic 2',3'-nucleoside monophosphate
-
r