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Literature summary for 4.6.1.18 extracted from

  • Carsana, A.; Furia, A.; Calabria, R.; Palmieri, M.
    In vitro synthesis of pig pancreas ribonuclease (1985), Biochim. Biophys. Acta, 825, 299-302.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
13790
-
pancreas, amino acid composition, in vitro synthesized enzyme, precursor protein has a 7000fold higher molecular weight Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RNA + H2O Sus scrofa endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA 3'-phosphomononucleotides + 3'-phosphooligonucleotides
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclic 2',3'-nucleoside monophosphate + H2O second step of hydrolysis is irreversible Sus scrofa 3'-phosphomononucleotides
-
ir
RNA + H2O endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in Cp or Up with 2',3'-cyclic phosphate intermediates, e.g. tRNA, 18S and 28S rRNA, yeast RNA,4.5S RNA Sus scrofa 3'-phosphomononucleotides + 3'-phosphooligonucleotides
-
?
RNA + H2O first step of hydrolysis is reversible Sus scrofa cyclic 2',3'-nucleoside monophosphate
-
r