Literature summary for 4.6.1.17 extracted from

Hover, B.M.; Lilla, E.A.; Yokoyama, K.
Mechanistic investigation of cPMP synthase in molybdenum cofactor biosynthesis using an uncleavable substrate analogue (2015), Biochemistry, 54, 7229-7236 .

Search for more literature for 4.6.1.17

Inhibitors

Inhibitors	Comment	Organism	Structure
(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-P-CH2-PP	compound is converted to an analogue of the MoaC reaction intermediate and causes mechanism-based inhibition. the reaction product harbors an acid-labile triaminopyrimidinone base without an established pyranopterin structure and forms a tight complex with MoaC likely through a covalent linkage	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(8S)-3',8-cyclo-7,8-dihydroguanosine-P[CH2]PP	-	Escherichia coli	cyclic pyranopterin phosphate + diphosphate	-	?

Synonyms

Synonyms	Comment	Organism
MoaC	-	Escherichia coli

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Release 2023.1 (January 2023)